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Overview of treatment results in 2024

Treatment Cycles and Methods

In 2024, the MVZ conducted over 2,644 assisted reproduction (ART) treatment cycles. These included:

  • 1,329 follicular punctures for IVF or ICSI therapies
  • 284 follicular punctures for social or medical egg freezing
  • 1,031 thaw cycles

Almost half of all treatments were performed with cryopreserved gametes.

 

Pregnancy Rates
  • For IVF and ICSI therapies, average pregnancy rates of 40% were achieved across all age groups.
  • For so-called “ideal patients” (≤ 37 years, first treatment cycle, AMH ≥ 1.0, at least 4 pronuclear stages, use of fresh or cryopreserved sperm), the pregnancy rate in ICSI therapies was 54.3%.

Success rates decline continuously with increasing female age, making age a decisive factor for treatment outcomes.

 

Multiple Pregnancies and Quality Goals

In addition to high pregnancy rates, reducing multiple pregnancies has become a central quality criterion. The goal is the birth of a healthy child with minimal risk.

  • After transfer of 2 blastocysts, the multiple pregnancy rate across all age groups was 27%.
  • For twin pregnancies, the preterm birth rate in 2022 was 76.5% (German IVF Register DIR).
  • To avoid multiple pregnancies, single embryo transfer (SET) is increasingly used.
  • In 2024, 86% of our fresh transfers were performed as SET, achieving pregnancy rates equivalent to the transfer of two blastocysts.

 

Embryonic Development and Laboratory Techniques

Embryo development on day two or three is only partially predictable. Physiologically, implantation occurs at the blastocyst stage in the uterine cavity.

  • In the laboratory, embryonic development is monitored over five days to transfer the optimal blastocyst on day 5.
  • By using state-of-the-art laboratory technology, particularly the EmbryoScope incubator system with AI-assisted assessment (IDA score), high pregnancy rates can be achieved with single embryo transfer.
Pregnancy rate/embryo transfer 2024 by age group in years

Sources
1 Statistics MVZ PAN Institute Interdisciplinary Fertility Centre 2025
Journal of Reproductive Medicine and Endocrinology