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Assisted hatching

Thinning of the zona pellucida using laser technology

During the development of the egg cell into the blastocyst, an embryo is surrounded by a shell, the zona pellucida. This protects it until shortly before implantation in the uterus. Then due to special enzymes and the pressure of the growing embryo, the zona pellucida ruptures and the embryo hatches.

Facilitation of embryo hatching

Assisted hatching was developed with the assumption that through the in vitro culture or cryopreservation, this shell is hardened. Today, the safest method for the partial thinning of the zona pellucida is laser technology. However, the clinical significance of the so-called assisted hatching has not been fully established at this time.